BDBM50167661 (Z)-3-[4-(4-Amino-2-trifluoromethyl-phenoxy)-phenyl]-2-(3-cyclopentyl-propionylamino)-acrylic acid::CHEMBL192112

SMILES: Nc1ccc(Oc2ccc(\C=C(/NC(=O)CCC3CCCC3)C(O)=O)cc2)c(c1)C(F)(F)F

InChI Key: InChIKey=JJPVVTHIKUZJTK-MOSHPQCFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50167661   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50167661 ((Z)-3-[4-(4-Amino-2-trifluoromethyl-phenoxy)-pheny...) Show SMILES Nc1ccc(Oc2ccc(\C=C(/NC(=O)CCC3CCCC3)C(O)=O)cc2)c(c1)C(F)(F)F Show InChI InChI=1S/C24H25F3N2O4/c25-24(26,27)19-14-17(28)8-11-21(19)33-18-9-5-16(6-10-18)13-20(23(31)32)29-22(30)12-7-15-3-1-2-4-15/h5-6,8-11,13-15H,1-4,7,12,28H2,(H,29,30)(H,31,32)/b20-13-	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research & Development Curated by ChEMBL					Assay Description Inhibitory concentration against RNA dependent RNA polymerase Nonstructural protein 5B (HCV NS5B polymerase) in Hepatitis C virus				Bioorg Med Chem Lett 15: 2812-8 (2005) Article DOI: 10.1016/j.bmcl.2005.03.106 BindingDB Entry DOI: 10.7270/Q26M36C7
					More data for this Ligand-Target Pair