BDBM50167669 CHEMBL372277::N-{(Z)-1-Benzylcarbamoyl-2-[4-(2-bromo-phenoxy)-phenyl]-vinyl}-benzamide

SMILES: Brc1ccccc1Oc1ccc(\C=C(/NC(=O)c2ccccc2)C(=O)NCc2ccccc2)cc1

InChI Key: InChIKey=OUGLSSSOZLDMLE-XHPQRKPJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50167669   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50167669 (CHEMBL372277 | N-{(Z)-1-Benzylcarbamoyl-2-[4-(2-br...) Show SMILES Brc1ccccc1Oc1ccc(\C=C(/NC(=O)c2ccccc2)C(=O)NCc2ccccc2)cc1 Show InChI InChI=1S/C29H23BrN2O3/c30-25-13-7-8-14-27(25)35-24-17-15-21(16-18-24)19-26(32-28(33)23-11-5-2-6-12-23)29(34)31-20-22-9-3-1-4-10-22/h1-19H,20H2,(H,31,34)(H,32,33)/b26-19-	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research & Development Curated by ChEMBL					Assay Description Inhibitory concentration against RNA dependent RNA polymerase Nonstructural protein 5B (HCV NS5B polymerase) in Hepatitis C virus				Bioorg Med Chem Lett 15: 2812-8 (2005) Article DOI: 10.1016/j.bmcl.2005.03.106 BindingDB Entry DOI: 10.7270/Q26M36C7
					More data for this Ligand-Target Pair