BDBM50167807 1-(4-fluorophenyl)-4a-methyl-4'-vinyl-(4'S,4aS,5'R)-spiro[1,4,4a,5,6,7-hexahydrocyclopenta[f]indazole-5,2'-(dihydro[1,3]dioxolane)]::CHEMBL194059

SMILES: C[C@]12Cc3cnn(c3C=C1CC[C@]21OC[C@@H](O1)C=C)-c1ccc(F)cc1

InChI Key: InChIKey=PBYIXRTVEABHKD-SESVDKBCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50167807   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50167807 (1-(4-fluorophenyl)-4a-methyl-4'-vinyl-(4'S,4aS,5'R...) Show SMILES C[C@]12Cc3cnn(c3C=C1CC[C@]21OC[C@@H](O1)C=C)-c1ccc(F)cc1 |c:9| Show InChI InChI=1S/C21H21FN2O2/c1-3-18-13-25-21(26-18)9-8-15-10-19-14(11-20(15,21)2)12-23-24(19)17-6-4-16(22)5-7-17/h3-7,10,12,18H,1,8-9,11,13H2,2H3/t18-,20-,21+/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human glucocorticoid receptor alpha isoform				Bioorg Med Chem Lett 15: 2926-31 (2005) Article DOI: 10.1016/j.bmcl.2005.03.027 BindingDB Entry DOI: 10.7270/Q2X34X0Q
					More data for this Ligand-Target Pair