BDBM50167817 1-(4-fluorophenyl)-4a-methyl-4',5'-diphenyl-(4'R,4aS,5'R)-spiro[4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazole-5,2'-(dihydro[1,3]dioxolane)]::CHEMBL193798

SMILES: C[C@]12Cc3cnn(c3C=C1CCCC21O[C@@H]([C@H](O1)c1ccccc1)c1ccccc1)-c1ccc(F)cc1

InChI Key: InChIKey=QBIJYIWFYANERG-OLUZHXLYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50167817   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50167817 (1-(4-fluorophenyl)-4a-methyl-4',5'-diphenyl-(4'R,4...) Show SMILES C[C@]12Cc3cnn(c3C=C1CCCC21O[C@@H]([C@H](O1)c1ccccc1)c1ccccc1)-c1ccc(F)cc1 |c:9| Show InChI InChI=1S/C32H29FN2O2/c1-31-20-24-21-34-35(27-16-14-26(33)15-17-27)28(24)19-25(31)13-8-18-32(31)36-29(22-9-4-2-5-10-22)30(37-32)23-11-6-3-7-12-23/h2-7,9-12,14-17,19,21,29-30H,8,13,18,20H2,1H3/t29-,30-,31+/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human glucocorticoid receptor alpha isoform				Bioorg Med Chem Lett 15: 2926-31 (2005) Article DOI: 10.1016/j.bmcl.2005.03.027 BindingDB Entry DOI: 10.7270/Q2X34X0Q
					More data for this Ligand-Target Pair