BDBM50168035 CHEMBL3799859

SMILES: Clc1ccc(CN2CCn3nc(cc3C2=O)C(=O)NCc2cccnc2)cc1Cl

InChI Key: InChIKey=WGPLRYUJBOMVDZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50168035   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM50168035 (CHEMBL3799859) Show SMILES Clc1ccc(CN2CCn3nc(cc3C2=O)C(=O)NCc2cccnc2)cc1Cl Show InChI InChI=1S/C20H17Cl2N5O2/c21-15-4-3-13(8-16(15)22)12-26-6-7-27-18(20(26)29)9-17(25-27)19(28)24-11-14-2-1-5-23-10-14/h1-5,8-10H,6-7,11-12H2,(H,24,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Charles River Laboratories Curated by ChEMBL					Assay Description Inhibition of human NAMPT using NAM as substrate assessed as NMN formation preincubated for 5 mins followed by substrate addition measured after 15 m...				Bioorg Med Chem Lett 26: 2920-2926 (2016) BindingDB Entry DOI: 10.7270/Q2RR215F
					More data for this Ligand-Target Pair