null

SMILES: OC(=O)CCNC(=O)c1ccc2C(CCc2c1)n1nc(cc1-c1ccccc1)-c1cc(Cl)cc(Cl)c1

InChI Key: InChIKey=RTNIRCAEPMWZSM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50168078   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon receptor (Homo sapiens (Human))	BDBM50168078 (CHEMBL3799820) Show SMILES OC(=O)CCNC(=O)c1ccc2C(CCc2c1)n1nc(cc1-c1ccccc1)-c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C28H23Cl2N3O3/c29-21-13-20(14-22(30)15-21)24-16-26(17-4-2-1-3-5-17)33(32-24)25-9-7-18-12-19(6-8-23(18)25)28(36)31-11-10-27(34)35/h1-6,8,12-16,25H,7,9-11H2,(H,31,36)(H,34,35)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from wild type human glucagon receptor expressed in CHO-K1 cells after 3 hrs by scintillation counting method				Bioorg Med Chem 24: 2852-63 (2016) BindingDB Entry DOI: 10.7270/Q27P919J
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50168078 (CHEMBL3799820) Show SMILES OC(=O)CCNC(=O)c1ccc2C(CCc2c1)n1nc(cc1-c1ccccc1)-c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C28H23Cl2N3O3/c29-21-13-20(14-22(30)15-21)24-16-26(17-4-2-1-3-5-17)33(32-24)25-9-7-18-12-19(6-8-23(18)25)28(36)31-11-10-27(34)35/h1-6,8,12-16,25H,7,9-11H2,(H,31,36)(H,34,35)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica Curated by ChEMBL					Assay Description Antagonist activity at wild type human glucagon receptor expressed in HEK293T cells assessed as inhibition of glucagon-induced cAMP accumulation incu...				Bioorg Med Chem 24: 2852-63 (2016) BindingDB Entry DOI: 10.7270/Q27P919J
					More data for this Ligand-Target Pair