BDBM50168444 4-(2-{2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenoxy}-ethyl)-morpholine; hydrochloride::CHEMBL537189

SMILES: COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1OCCN1CCOCC1

InChI Key: InChIKey=ZAEWLANEOQOOEN-WAYWQWQTSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50168444   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tubulin beta-1 chain (Homo sapiens (Human))	BDBM50168444 (4-(2-{2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1OCCN1CCOCC1 Show InChI InChI=1S/C24H31NO6/c1-26-20-8-7-18(15-21(20)31-14-11-25-9-12-30-13-10-25)5-6-19-16-22(27-2)24(29-4)23(17-19)28-3/h5-8,15-17H,9-14H2,1-4H3/b6-5-	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree C				J Med Chem 48: 4087-99 (2005) Article DOI: 10.1021/jm0205797 BindingDB Entry DOI: 10.7270/Q23B60XC
					More data for this Ligand-Target Pair