BDBM50168513 CHEMBL434156::N-(1-Benzo[1,3]dioxol-5-ylmethyl-piperidin-3-yl)-2,5-dimethoxy-benzamide

SMILES: COc1ccc(OC)c(c1)C(=O)NC1CCCN(Cc2ccc3OCOc3c2)C1

InChI Key: InChIKey=UDICITPBHFUUCH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50168513   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Mus musculus)	BDBM50168513 (CHEMBL434156 | N-(1-Benzo[1,3]dioxol-5-ylmethyl-pi...) Show SMILES COc1ccc(OC)c(c1)C(=O)NC1CCCN(Cc2ccc3OCOc3c2)C1 Show InChI InChI=1S/C22H26N2O5/c1-26-17-6-8-19(27-2)18(11-17)22(25)23-16-4-3-9-24(13-16)12-15-5-7-20-21(10-15)29-14-28-20/h5-8,10-11,16H,3-4,9,12-14H2,1-2H3,(H,23,25)	Reactome pathway KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration required for binding affinity against mouse MCHr1 competing human neuronal IMR32 cells receptor in a radiometric binding ass...				Bioorg Med Chem Lett 15: 3412-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.023 BindingDB Entry DOI: 10.7270/Q26D5SHR
					More data for this Ligand-Target Pair