BDBM50168519 CHEMBL186825::N-(1-Benzo[1,3]dioxol-5-ylmethyl-piperidin-4-yl)-2-(3'-methoxy-biphenyl-4-yl)-acetamide

SMILES: COc1cccc(c1)-c1ccc(CC(=O)NC2CCN(Cc3ccc4OCOc4c3)CC2)cc1

InChI Key: InChIKey=IYYOXVFZICYJPU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50168519   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Mus musculus)	BDBM50168519 (CHEMBL186825 | N-(1-Benzo[1,3]dioxol-5-ylmethyl-pi...) Show SMILES COc1cccc(c1)-c1ccc(CC(=O)NC2CCN(Cc3ccc4OCOc4c3)CC2)cc1 Show InChI InChI=1S/C28H30N2O4/c1-32-25-4-2-3-23(17-25)22-8-5-20(6-9-22)16-28(31)29-24-11-13-30(14-12-24)18-21-7-10-26-27(15-21)34-19-33-26/h2-10,15,17,24H,11-14,16,18-19H2,1H3,(H,29,31)	Reactome pathway KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration required for binding affinity against mouse MCHr1 competing human neuronal IMR32 cells receptor in a radiometric binding ass...				Bioorg Med Chem Lett 15: 3412-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.023 BindingDB Entry DOI: 10.7270/Q26D5SHR
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Mus musculus)	BDBM50168519 (CHEMBL186825 | N-(1-Benzo[1,3]dioxol-5-ylmethyl-pi...) Show SMILES COc1cccc(c1)-c1ccc(CC(=O)NC2CCN(Cc3ccc4OCOc4c3)CC2)cc1 Show InChI InChI=1S/C28H30N2O4/c1-32-25-4-2-3-23(17-25)22-8-5-20(6-9-22)16-28(31)29-24-11-13-30(14-12-24)18-21-7-10-26-27(15-21)34-19-33-26/h2-10,15,17,24H,11-14,16,18-19H2,1H3,(H,29,31)	Reactome pathway KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	890	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration required for functional antagonism of MCH mediated Ca+2 release competing human IMR32 cells receptor in a FLIPRTM based assa...				Bioorg Med Chem Lett 15: 3412-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.023 BindingDB Entry DOI: 10.7270/Q26D5SHR
					More data for this Ligand-Target Pair