BDBM50168723 1-[2-[((R)-1-Amino-indane-2-carbonyl)-amino]-3-(4-chloro-phenyl)-propionyl]-4-cyclohexyl-piperidine-4-carboxylic acid tert-butylamide::CHEMBL187990

SMILES: CC(C)(C)NC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)C1Cc2ccccc2C1N)C1CCCCC1

InChI Key: InChIKey=MRFZKAWUCKFKJV-FNPAZFQPSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50168723   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 3 (Homo sapiens (Human))	BDBM50168723 (1-[2-[((R)-1-Amino-indane-2-carbonyl)-amino]-3-(4-...) Show SMILES CC(C)(C)NC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)C1Cc2ccccc2C1N)C1CCCCC1 Show InChI InChI=1S/C35H47ClN4O3/c1-34(2,3)39-33(43)35(25-10-5-4-6-11-25)17-19-40(20-18-35)32(42)29(21-23-13-15-26(36)16-14-23)38-31(41)28-22-24-9-7-8-12-27(24)30(28)37/h7-9,12-16,25,28-30H,4-6,10-11,17-22,37H2,1-3H3,(H,38,41)(H,39,43)/t28?,29-,30?/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Concentration required for 50% inhibition by displacement of of [125I]NDP-alpha-MSH of human MC3R expressed in CHO cells				Bioorg Med Chem Lett 15: 3430-3 (2005) Article DOI: 10.1016/j.bmcl.2005.05.012 BindingDB Entry DOI: 10.7270/Q2959H2N
					More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM50168723 (1-[2-[((R)-1-Amino-indane-2-carbonyl)-amino]-3-(4-...) Show SMILES CC(C)(C)NC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)C1Cc2ccccc2C1N)C1CCCCC1 Show InChI InChI=1S/C35H47ClN4O3/c1-34(2,3)39-33(43)35(25-10-5-4-6-11-25)17-19-40(20-18-35)32(42)29(21-23-13-15-26(36)16-14-23)38-31(41)28-22-24-9-7-8-12-27(24)30(28)37/h7-9,12-16,25,28-30H,4-6,10-11,17-22,37H2,1-3H3,(H,38,41)(H,39,43)/t28?,29-,30?/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Concentration required for 50% inhibition by displacement of of [125I]NDP-alpha-MSH of human MC1R expressed in CHO cells				Bioorg Med Chem Lett 15: 3430-3 (2005) Article DOI: 10.1016/j.bmcl.2005.05.012 BindingDB Entry DOI: 10.7270/Q2959H2N
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50168723 (1-[2-[((R)-1-Amino-indane-2-carbonyl)-amino]-3-(4-...) Show SMILES CC(C)(C)NC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)C1Cc2ccccc2C1N)C1CCCCC1 Show InChI InChI=1S/C35H47ClN4O3/c1-34(2,3)39-33(43)35(25-10-5-4-6-11-25)17-19-40(20-18-35)32(42)29(21-23-13-15-26(36)16-14-23)38-31(41)28-22-24-9-7-8-12-27(24)30(28)37/h7-9,12-16,25,28-30H,4-6,10-11,17-22,37H2,1-3H3,(H,38,41)(H,39,43)/t28?,29-,30?/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Concentration required for 50% inhibition by displacement of of [125I]NDP-alpha-MSH of human MC4R expressed in CHO cells				Bioorg Med Chem Lett 15: 3430-3 (2005) Article DOI: 10.1016/j.bmcl.2005.05.012 BindingDB Entry DOI: 10.7270/Q2959H2N
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (MC5R) (Homo sapiens (Human))	BDBM50168723 (1-[2-[((R)-1-Amino-indane-2-carbonyl)-amino]-3-(4-...) Show SMILES CC(C)(C)NC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)C1Cc2ccccc2C1N)C1CCCCC1 Show InChI InChI=1S/C35H47ClN4O3/c1-34(2,3)39-33(43)35(25-10-5-4-6-11-25)17-19-40(20-18-35)32(42)29(21-23-13-15-26(36)16-14-23)38-31(41)28-22-24-9-7-8-12-27(24)30(28)37/h7-9,12-16,25,28-30H,4-6,10-11,17-22,37H2,1-3H3,(H,38,41)(H,39,43)/t28?,29-,30?/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Concentration required for 50% inhibition by displacement of of [125I]NDP-alpha-MSH of human MC5R expressed in CHO cells				Bioorg Med Chem Lett 15: 3430-3 (2005) Article DOI: 10.1016/j.bmcl.2005.05.012 BindingDB Entry DOI: 10.7270/Q2959H2N
					More data for this Ligand-Target Pair