BDBM50169307 2-Furan-2-yl-7-phenyl-[1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine::CHEMBL174850

SMILES: Nc1nc(cc2nc(nn12)-c1ccco1)-c1ccccc1

InChI Key: InChIKey=NIZRJAQNDZMDLX-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50169307   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50169307 (2-Furan-2-yl-7-phenyl-[1,2,4]triazolo[1,5-c]pyrimi...) Show SMILES Nc1nc(cc2nc(nn12)-c1ccco1)-c1ccccc1 Show InChI InChI=1S/C15H11N5O/c16-15-17-11(10-5-2-1-3-6-10)9-13-18-14(19-20(13)15)12-7-4-8-21-12/h1-9H,(H2,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity against human adenosine A2A receptor				Bioorg Med Chem Lett 21: 2497-501 (2011) Article DOI: 10.1016/j.bmcl.2011.02.045 BindingDB Entry DOI: 10.7270/Q21Z44Q5
					More data for this Ligand-Target Pair
Adenosine Receptors A2a (A2a) (Rattus norvegicus (rat))	BDBM50169307 (2-Furan-2-yl-7-phenyl-[1,2,4]triazolo[1,5-c]pyrimi...) Show SMILES Nc1nc(cc2nc(nn12)-c1ccco1)-c1ccccc1 Show InChI InChI=1S/C15H11N5O/c16-15-17-11(10-5-2-1-3-6-10)9-13-18-14(19-20(13)15)12-7-4-8-21-12/h1-9H,(H2,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description In vitro ability to displace [3H]-SCH-58,261 from A2A adenosine receptor in Rat				Bioorg Med Chem Lett 15: 3670-4 (2005) Article DOI: 10.1016/j.bmcl.2005.05.086 BindingDB Entry DOI: 10.7270/Q279446R
					More data for this Ligand-Target Pair