BDBM50169369 3,5-Dichloro-N-[4-(3'-cyano-biphenyl-4-yl)-1-methyl-piperidin-4-ylmethyl]-benzenesulfonamide::CHEMBL179216

SMILES: CN1CCC(CNS(=O)(=O)c2cc(Cl)cc(Cl)c2)(CC1)c1ccc(cc1)-c1cccc(c1)C#N

InChI Key: InChIKey=ZKOBLZJJRRPTOY-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50169369   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50169369 (3,5-Dichloro-N-[4-(3'-cyano-biphenyl-4-yl)-1-methy...) Show SMILES CN1CCC(CNS(=O)(=O)c2cc(Cl)cc(Cl)c2)(CC1)c1ccc(cc1)-c1cccc(c1)C#N Show InChI InChI=1S/C26H25Cl2N3O2S/c1-31-11-9-26(10-12-31,18-30-34(32,33)25-15-23(27)14-24(28)16-25)22-7-5-20(6-8-22)21-4-2-3-19(13-21)17-29/h2-8,13-16,30H,9-12,18H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	281	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacopeia Drug Discovery, Inc. Curated by ChEMBL					Assay Description Ability to displace [125-I]-MCH()0.5 nM from human MCH1R(2.5 uM) expressed in CHO cells				Bioorg Med Chem Lett 15: 3696-700 (2005) Article DOI: 10.1016/j.bmcl.2005.05.085 BindingDB Entry DOI: 10.7270/Q2ZS2W16
					More data for this Ligand-Target Pair