BDBM50169385 1-(3,5-Dichloro-phenyl)-3-(1-methyl-4-p-tolyl-piperidin-4-ylmethyl)-urea::CHEMBL175874

SMILES: CN1CCC(CNC(=O)Nc2cc(Cl)cc(Cl)c2)(CC1)c1ccc(C)cc1

InChI Key: InChIKey=XWAIJWKTDQPUKU-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50169385   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50169385 (1-(3,5-Dichloro-phenyl)-3-(1-methyl-4-p-tolyl-pipe...) Show SMILES CN1CCC(CNC(=O)Nc2cc(Cl)cc(Cl)c2)(CC1)c1ccc(C)cc1 Show InChI InChI=1S/C21H25Cl2N3O/c1-15-3-5-16(6-4-15)21(7-9-26(2)10-8-21)14-24-20(27)25-19-12-17(22)11-18(23)13-19/h3-6,11-13H,7-10,14H2,1-2H3,(H2,24,25,27)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacopeia Drug Discovery, Inc. Curated by ChEMBL					Assay Description Ability to displace [125-I]-MCH()0.5 nM from human MCH1R(2.5 uM) expressed in CHO cells				Bioorg Med Chem Lett 15: 3696-700 (2005) Article DOI: 10.1016/j.bmcl.2005.05.085 BindingDB Entry DOI: 10.7270/Q2ZS2W16
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50169385 (1-(3,5-Dichloro-phenyl)-3-(1-methyl-4-p-tolyl-pipe...) Show SMILES CN1CCC(CNC(=O)Nc2cc(Cl)cc(Cl)c2)(CC1)c1ccc(C)cc1 Show InChI InChI=1S/C21H25Cl2N3O/c1-15-3-5-16(6-4-15)21(7-9-26(2)10-8-21)14-24-20(27)25-19-12-17(22)11-18(23)13-19/h3-6,11-13H,7-10,14H2,1-2H3,(H2,24,25,27)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of Science and Technology Curated by ChEMBL					Assay Description Antagonist activity at MCHR1 (unknown origin) expressed in CHO cells co-expressing aequorin incubated for 10 mins by luminescence assay				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126741
					More data for this Ligand-Target Pair