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BDBM50169395 1-[1-Butyl-4-(3'-cyano-biphenyl-4-yl)-piperidin-4-ylmethyl]-3-(3,5-dichloro-phenyl)-urea::CHEMBL361821

SMILES: CCCCN1CCC(CNC(=O)Nc2cc(Cl)cc(Cl)c2)(CC1)c1ccc(cc1)-c1cccc(c1)C#N

InChI Key: InChIKey=BIMBTDFFXARQLX-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50169395   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor


(Homo sapiens (Human))		BDBM50169395
PNG
(1-[1-Butyl-4-(3'-cyano-biphenyl-4-yl)-piperidin-4-...)
Show SMILES CCCCN1CCC(CNC(=O)Nc2cc(Cl)cc(Cl)c2)(CC1)c1ccc(cc1)-c1cccc(c1)C#N
Show InChI InChI=1S/C30H32Cl2N4O/c1-2-3-13-36-14-11-30(12-15-36,21-34-29(37)35-28-18-26(31)17-27(32)19-28)25-9-7-23(8-10-25)24-6-4-5-22(16-24)20-33/h4-10,16-19H,2-3,11-15,21H2,1H3,(H2,34,35,37)
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Article
PubMed
 11n/an/an/an/an/an/an/an/a



Pharmacopeia Drug Discovery, Inc.

Curated by ChEMBL


Assay Description
Ability to displace [125-I]-MCH()0.5 nM from human MCH1R(2.5 uM) expressed in CHO cells

Bioorg Med Chem Lett 15: 3696-700 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.085
BindingDB Entry DOI: 10.7270/Q2ZS2W16
More data for this
Ligand-Target Pair