BDBM50169517 CHEMBL190745::Cyclopropylmethyl-[2-trifluoromethyl-9-(2,4,6-trimethyl-phenyl)-9H-benzo[d]imidazo[1,2-a]imidazol-3-ylmethyl]-(3,3,3-trifluoro-propyl)-amine

SMILES: Cc1cc(C)c(c(C)c1)-n1c2ccccc2n2c(CN(CCC(F)(F)F)CC3CC3)c(nc12)C(F)(F)F

InChI Key: InChIKey=IAPBVJCDTHIXQJ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50169517   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50169517 (CHEMBL190745 | Cyclopropylmethyl-[2-trifluoromethy...) Show SMILES Cc1cc(C)c(c(C)c1)-n1c2ccccc2n2c(CN(CCC(F)(F)F)CC3CC3)c(nc12)C(F)(F)F |(5.88,-11.87,;4.79,-10.77,;5.21,-9.28,;4.13,-8.18,;4.54,-6.71,;2.65,-8.58,;2.23,-10.07,;.73,-10.44,;3.3,-11.17,;1.57,-7.48,;1.82,-5.96,;3.11,-5.14,;3.04,-3.6,;1.67,-2.88,;.38,-3.72,;.45,-5.25,;-.65,-6.33,;-2.19,-6.56,;-3.27,-5.46,;-2.86,-3.98,;-3.94,-2.87,;-3.54,-1.39,;-4.61,-.29,;-5.6,.72,;-4.43,1.32,;-6.21,-.43,;-1.37,-3.58,;-.97,-2.1,;-1.35,-.61,;.12,-1.03,;-2.44,-8.09,;-1.07,-8.81,;.03,-7.71,;-3.83,-8.78,;-4.19,-10.35,;-5.08,-9.41,;-5.3,-8.11,)| Show InChI InChI=1S/C27H28F6N4/c1-16-12-17(2)23(18(3)13-16)37-21-7-5-4-6-20(21)36-22(24(27(31,32)33)34-25(36)37)15-35(14-19-8-9-19)11-10-26(28,29)30/h4-7,12-13,19H,8-11,14-15H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity for human corticotropin releasing factor receptor 1				Bioorg Med Chem Lett 15: 4029-32 (2005) Article DOI: 10.1016/j.bmcl.2005.06.028 BindingDB Entry DOI: 10.7270/Q2B27TS9
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