BDBM50169563 7-(2-Bromo-4,6-dimethyl-phenyl)-2-ethyl-6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-carboxylic acid cyclopropylmethyl-(2,2,2-trifluoro-ethyl)-amide::CHEMBL182482

SMILES: CCc1nc2N(CCn2c1C(=O)N(CC1CC1)CC(F)(F)F)c1c(C)cc(C)cc1Br

InChI Key: InChIKey=VUGGREOGOSQFSN-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50169563   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50169563 (7-(2-Bromo-4,6-dimethyl-phenyl)-2-ethyl-6,7-dihydr...) Show SMILES CCc1nc2N(CCn2c1C(=O)N(CC1CC1)CC(F)(F)F)c1c(C)cc(C)cc1Br Show InChI InChI=1S/C22H26BrF3N4O/c1-4-17-19(20(31)28(11-15-5-6-15)12-22(24,25)26)30-8-7-29(21(30)27-17)18-14(3)9-13(2)10-16(18)23/h9-10,15H,4-8,11-12H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]-Tyr-o- CRF from human corticotropin releasing factor receptor 1 expressed in IMR-32 cells				Bioorg Med Chem Lett 15: 3870-3 (2005) Article DOI: 10.1016/j.bmcl.2005.05.117 BindingDB Entry DOI: 10.7270/Q269733T
					More data for this Ligand-Target Pair