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BDBM50169572 7-(2-Bromo-4-isopropyl-phenyl)-2-ethyl-6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-carboxylic acid cyclopropylmethyl-propyl-amide::CHEMBL182624

SMILES: CCCN(CC1CC1)C(=O)c1c(CC)nc2N(CCn12)c1ccc(cc1Br)C(C)C

InChI Key: InChIKey=AHFGQJRGKXTSDO-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50169572   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))		BDBM50169572
PNG
(7-(2-Bromo-4-isopropyl-phenyl)-2-ethyl-6,7-dihydro...)
Show SMILES CCCN(CC1CC1)C(=O)c1c(CC)nc2N(CCn12)c1ccc(cc1Br)C(C)C
Show InChI InChI=1S/C24H33BrN4O/c1-5-11-27(15-17-7-8-17)23(30)22-20(6-2)26-24-28(12-13-29(22)24)21-10-9-18(16(3)4)14-19(21)25/h9-10,14,16-17H,5-8,11-13,15H2,1-4H3
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Article
PubMed
 1.56E+3n/an/an/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Displacement of [125I]-Tyr-o- CRF from human corticotropin releasing factor receptor 1 expressed in IMR-32 cells

Bioorg Med Chem Lett 15: 3870-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.117
BindingDB Entry DOI: 10.7270/Q269733T
More data for this
Ligand-Target Pair