BDBM50169576 2-Ethyl-7-(2,4,6-trimethyl-phenyl)-6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-carboxylic acid propyl-(2,2,2-trifluoro-ethyl)-amide::CHEMBL369341

SMILES: CCCN(CC(F)(F)F)C(=O)c1c(CC)nc2N(CCn12)c1c(C)cc(C)cc1C

InChI Key: InChIKey=LQEITOXZZODRDN-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50169576   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50169576 (2-Ethyl-7-(2,4,6-trimethyl-phenyl)-6,7-dihydro-5H-...) Show SMILES CCCN(CC(F)(F)F)C(=O)c1c(CC)nc2N(CCn12)c1c(C)cc(C)cc1C Show InChI InChI=1S/C22H29F3N4O/c1-6-8-27(13-22(23,24)25)20(30)19-17(7-2)26-21-28(9-10-29(19)21)18-15(4)11-14(3)12-16(18)5/h11-12H,6-10,13H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	61	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]-Tyr-o- CRF from human corticotropin releasing factor receptor 1 expressed in IMR-32 cells				Bioorg Med Chem Lett 15: 3870-3 (2005) Article DOI: 10.1016/j.bmcl.2005.05.117 BindingDB Entry DOI: 10.7270/Q269733T
					More data for this Ligand-Target Pair