BDBM50169611 CHEMBL3805554

SMILES: [H][C@]12C[C@@H](O)[C@H](COc3cccc(C)c3)[C@@]1([H])CC[C@@H](O2)c1nc(cs1)C(O)=O

InChI Key: InChIKey=VVWFWDWTNZZBES-TWPTVVAISA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50169611   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50169611 (CHEMBL3805554) Show SMILES [H][C@]12C[C@@H](O)[C@H](COc3cccc(C)c3)[C@@]1([H])CC[C@@H](O2)c1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C20H23NO5S/c1-11-3-2-4-12(7-11)25-9-14-13-5-6-17(26-18(13)8-16(14)22)19-21-15(10-27-19)20(23)24/h2-4,7,10,13-14,16-18,22H,5-6,8-9H2,1H3,(H,23,24)/t13-,14-,16-,17-,18+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at PK2-tagged human EP2 receptor expressed in HEK293 cells assessed as induction of EA-tagged beta-arrestin recruitment incubated fo...				ACS Med Chem Lett 7: 306-11 (2016) BindingDB Entry DOI: 10.7270/Q2125VKG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50169611 (CHEMBL3805554) Show SMILES [H][C@]12C[C@@H](O)[C@H](COc3cccc(C)c3)[C@@]1([H])CC[C@@H](O2)c1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C20H23NO5S/c1-11-3-2-4-12(7-11)25-9-14-13-5-6-17(26-18(13)8-16(14)22)19-21-15(10-27-19)20(23)24/h2-4,7,10,13-14,16-18,22H,5-6,8-9H2,1H3,(H,23,24)/t13-,14-,16-,17-,18+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	3.60	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at human EP2 receptor expressed in CHO cells assessed as increase in intracellular cAMP level after 30 mins by HTRF method				ACS Med Chem Lett 7: 306-11 (2016) BindingDB Entry DOI: 10.7270/Q2125VKG
					More data for this Ligand-Target Pair