BDBM50169646 6-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phenyl]-3-ethyl-1-propyl-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one::CHEMBL360086

SMILES: CCCn1nc(CC)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1

InChI Key: InChIKey=OAHFUXKBTDCSPE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50169646   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 1 (Homo sapiens (Human))	BDBM50169646 (6-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...) Show SMILES CCCn1nc(CC)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1 Show InChI InChI=1S/C23H32N6O4S/c1-5-10-29-22-20(18(6-2)26-29)23(30)25-21(24-22)17-15-16(8-9-19(17)33-7-3)34(31,32)28-13-11-27(4)12-14-28/h8-9,15H,5-7,10-14H2,1-4H3,(H,24,25,30)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
BAYER HealthCare AG Curated by ChEMBL					Assay Description Inhibition of phosphodiesterase 1				Bioorg Med Chem Lett 15: 3900-7 (2005) Article DOI: 10.1016/j.bmcl.2005.05.090 BindingDB Entry DOI: 10.7270/Q2XS5TWD
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50169646 (6-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...) Show SMILES CCCn1nc(CC)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1 Show InChI InChI=1S/C23H32N6O4S/c1-5-10-29-22-20(18(6-2)26-29)23(30)25-21(24-22)17-15-16(8-9-19(17)33-7-3)34(31,32)28-13-11-27(4)12-14-28/h8-9,15H,5-7,10-14H2,1-4H3,(H,24,25,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
BAYER HealthCare AG Curated by ChEMBL					Assay Description Inhibition of phosphodiesterase 5				Bioorg Med Chem Lett 15: 3900-7 (2005) Article DOI: 10.1016/j.bmcl.2005.05.090 BindingDB Entry DOI: 10.7270/Q2XS5TWD
					More data for this Ligand-Target Pair