BDBM50169785 (2-Hydroxy-3-phenoxy-propyl)-isopropyl-ammonium::(2-hydroxy-3-phenoxypropyl)(propan-2-yl)amine::1-Isopropylamino-3-phenoxy-propan-2-ol::CHEMBL7154
SMILES: CC(C)NCC(O)COc1ccccc1
InChI Key: InChIKey=ONXLHKFGTDDVLQ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50169785 ((2-Hydroxy-3-phenoxy-propyl)-isopropyl-ammonium | ...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Lausanne Curated by ChEMBL | Assay Description Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacement | J Med Chem 39: 126-34 (1996) Article DOI: 10.1021/jm950410b BindingDB Entry DOI: 10.7270/Q2VX0K7V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2D6 (Homo sapiens (Human)) | BDBM50169785 ((2-Hydroxy-3-phenoxy-propyl)-isopropyl-ammonium | ...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against recombinant human Cytochrome P450 2D6 (CYP2D6) after incubated for 45 minutes | Bioorg Med Chem Lett 15: 3816-20 (2005) Article DOI: 10.1016/j.bmcl.2005.06.007 BindingDB Entry DOI: 10.7270/Q2WS8SSG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-2 adrenergic receptor (GUINEA PIG) | BDBM50169785 ((2-Hydroxy-3-phenoxy-propyl)-isopropyl-ammonium | ...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 13.8 | n/a | n/a | n/a | n/a | n/a |
Universidad de Barcelona Curated by ChEMBL | Assay Description Antagonism of isoprenaline-induced relaxation of guinea pig tracheal chains, contracted with carbachol | J Med Chem 31: 2122-6 (1988) BindingDB Entry DOI: 10.7270/Q2J67J4Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-2 adrenergic receptor (BOVINE) | BDBM50169785 ((2-Hydroxy-3-phenoxy-propyl)-isopropyl-ammonium | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA) | J Med Chem 28: 1328-34 (1985) BindingDB Entry DOI: 10.7270/Q2HX1DZG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1 adrenergic receptor (GUINEA PIG) | BDBM50169785 ((2-Hydroxy-3-phenoxy-propyl)-isopropyl-ammonium | ...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a |
Universidad de Barcelona Curated by ChEMBL | Assay Description Beta-1 adrenergic receptor activitation measured by isoprenaline-induced positive inotropic effect in guinea pig left atrium | J Med Chem 31: 2122-6 (1988) BindingDB Entry DOI: 10.7270/Q2J67J4Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ADRB2 (BOVINE) | BDBM50169785 ((2-Hydroxy-3-phenoxy-propyl)-isopropyl-ammonium | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 5.37E+4 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA) | J Med Chem 28: 1328-34 (1985) BindingDB Entry DOI: 10.7270/Q2HX1DZG | |||||||||||
More data for this Ligand-Target Pair |