BDBM50169908 3-Cyclohexyl-1-[2-(4-dimethylamino-piperidin-1-yl)-2-oxo-ethyl]-2-vinyl-1H-indole-6-carboxylic acid::CHEMBL188969

SMILES: CN(C)C1CCN(CC1)C(=O)Cn1c(C=C)c(C2CCCCC2)c2ccc(cc12)C(O)=O

InChI Key: InChIKey=ZXFKERPRIISMJM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50169908   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50169908 (3-Cyclohexyl-1-[2-(4-dimethylamino-piperidin-1-yl)...) Show SMILES CN(C)C1CCN(CC1)C(=O)Cn1c(C=C)c(C2CCCCC2)c2ccc(cc12)C(O)=O Show InChI InChI=1S/C26H35N3O3/c1-4-22-25(18-8-6-5-7-9-18)21-11-10-19(26(31)32)16-23(21)29(22)17-24(30)28-14-12-20(13-15-28)27(2)3/h4,10-11,16,18,20H,1,5-9,12-15,17H2,2-3H3,(H,31,32)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
IRBM (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against by hepatitis C virus NS5B polymerase				J Med Chem 48: 4547-57 (2005) Article DOI: 10.1021/jm050056+ BindingDB Entry DOI: 10.7270/Q24B30VN
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