BDBM50169974 (2Z)-1,3-benzothiazol-2(3H)-ylidene[2-(dimethylamino)pyrimidin-4-yl]acetonitrile::CHEMBL190380

SMILES: CN(C)c1nccc(n1)C(C#N)c1nc2ccccc2s1

InChI Key: InChIKey=XMKYPCSXRUFRAL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50169974   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
c-Jun N-terminal kinase 3 (Rattus norvegicus)	BDBM50169974 ((2Z)-1,3-benzothiazol-2(3H)-ylidene[2-(dimethylami...) Show SMILES CN(C)c1nccc(n1)C(C#N)c1nc2ccccc2s1 Show InChI InChI=1S/C15H13N5S/c1-20(2)15-17-8-7-11(19-15)10(9-16)14-18-12-5-3-4-6-13(12)21-14/h3-8,10H,1-2H3	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Serono Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of rat c-Jun N-terminal kinase 3				J Med Chem 48: 4596-607 (2005) Article DOI: 10.1021/jm0310986 BindingDB Entry DOI: 10.7270/Q2K9389G
					More data for this Ligand-Target Pair