null

SMILES: COCC(COC)Nc1cc(ccc1C(=O)Nc1n[nH]c2ccc(Cc3cc(F)cc(F)c3)cc12)N1CCN(C)CC1

InChI Key: InChIKey=NBVARWNYIREDGV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50170111   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50170111 (CHEMBL3805254) Show SMILES COCC(COC)Nc1cc(ccc1C(=O)Nc1n[nH]c2ccc(Cc3cc(F)cc(F)c3)cc12)N1CCN(C)CC1 Show InChI InChI=1S/C31H36F2N6O3/c1-38-8-10-39(11-9-38)25-5-6-26(29(17-25)34-24(18-41-2)19-42-3)31(40)35-30-27-15-20(4-7-28(27)36-37-30)12-21-13-22(32)16-23(33)14-21/h4-7,13-17,24,34H,8-12,18-19H2,1-3H3,(H2,35,36,37,40)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	99	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of recombinant ALK (unknown origin) in presence of gamma33-ATP				J Med Chem 59: 3392-408 (2016) BindingDB Entry DOI: 10.7270/Q27M09TG
					More data for this Ligand-Target Pair
Insulin receptor (Homo sapiens (Human))	BDBM50170111 (CHEMBL3805254) Show SMILES COCC(COC)Nc1cc(ccc1C(=O)Nc1n[nH]c2ccc(Cc3cc(F)cc(F)c3)cc12)N1CCN(C)CC1 Show InChI InChI=1S/C31H36F2N6O3/c1-38-8-10-39(11-9-38)25-5-6-26(29(17-25)34-24(18-41-2)19-42-3)31(40)35-30-27-15-20(4-7-28(27)36-37-30)12-21-13-22(32)16-23(33)14-21/h4-7,13-17,24,34H,8-12,18-19H2,1-3H3,(H2,35,36,37,40)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	1.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of IR (unknown origin) in presence of gamma33-ATP				J Med Chem 59: 3392-408 (2016) BindingDB Entry DOI: 10.7270/Q27M09TG
					More data for this Ligand-Target Pair