BDBM50170145 CHEMBL189128::{2-[(E)-2-(3,4-Dihydroxy-phenyl)-vinyl]-8-hydroxy-quinolin-7-yl}-(2-nitro-phenyl)-methanone

SMILES: Oc1ccc(\C=C\c2ccc3ccc(C(=O)c4ccccc4[N+]([O-])=O)c(O)c3n2)cc1O

InChI Key: InChIKey=GNBVLVYZMSESIQ-WEVVVXLNSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50170145   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50170145 (CHEMBL189128 | {2-[(E)-2-(3,4-Dihydroxy-phenyl)-vi...) Show SMILES Oc1ccc(\C=C\c2ccc3ccc(C(=O)c4ccccc4[N+]([O-])=O)c(O)c3n2)cc1O Show InChI InChI=1S/C24H16N2O6/c27-20-12-6-14(13-21(20)28)5-9-16-10-7-15-8-11-18(24(30)22(15)25-16)23(29)17-3-1-2-4-19(17)26(31)32/h1-13,27-28,30H/b9-5+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Unité Associée au CNRS Curated by ChEMBL					Assay Description In vitro inhibitory concentration against HIV-1 recombinant integrase activity in strand transfer assay				Bioorg Med Chem Lett 15: 4019-22 (2005) Article DOI: 10.1016/j.bmcl.2005.06.036 BindingDB Entry DOI: 10.7270/Q2GM86VW
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50170145 (CHEMBL189128 | {2-[(E)-2-(3,4-Dihydroxy-phenyl)-vi...) Show SMILES Oc1ccc(\C=C\c2ccc3ccc(C(=O)c4ccccc4[N+]([O-])=O)c(O)c3n2)cc1O Show InChI InChI=1S/C24H16N2O6/c27-20-12-6-14(13-21(20)28)5-9-16-10-7-15-8-11-18(24(30)22(15)25-16)23(29)17-3-1-2-4-19(17)26(31)32/h1-13,27-28,30H/b9-5+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Unité Associée au CNRS Curated by ChEMBL					Assay Description In vitro inhibitory concentration against HIV-1 recombinant integrase activity in standard 3'-processing assay				Bioorg Med Chem Lett 15: 4019-22 (2005) Article DOI: 10.1016/j.bmcl.2005.06.036 BindingDB Entry DOI: 10.7270/Q2GM86VW
					More data for this Ligand-Target Pair