BDBM50170149 (3,4-Difluoro-phenyl)-{2-[(E)-2-(3,4-dihydroxy-phenyl)-vinyl]-8-hydroxy-quinolin-7-yl}-methanone::CHEMBL189715

SMILES: Oc1ccc(\C=C\c2ccc3ccc(C(=O)c4ccc(F)c(F)c4)c(O)c3n2)cc1O

InChI Key: InChIKey=XCCXVYPNNNPHQC-LZCJLJQNSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50170149   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50170149 ((3,4-Difluoro-phenyl)-{2-[(E)-2-(3,4-dihydroxy-phe...) Show SMILES Oc1ccc(\C=C\c2ccc3ccc(C(=O)c4ccc(F)c(F)c4)c(O)c3n2)cc1O Show InChI InChI=1S/C24H15F2NO4/c25-18-9-5-15(12-19(18)26)23(30)17-8-4-14-3-7-16(27-22(14)24(17)31)6-1-13-2-10-20(28)21(29)11-13/h1-12,28-29,31H/b6-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Unité Associée au CNRS Curated by ChEMBL					Assay Description In vitro inhibitory concentration against HIV-1 recombinant integrase activity in standard 3'-processing assay				Bioorg Med Chem Lett 15: 4019-22 (2005) Article DOI: 10.1016/j.bmcl.2005.06.036 BindingDB Entry DOI: 10.7270/Q2GM86VW
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50170149 ((3,4-Difluoro-phenyl)-{2-[(E)-2-(3,4-dihydroxy-phe...) Show SMILES Oc1ccc(\C=C\c2ccc3ccc(C(=O)c4ccc(F)c(F)c4)c(O)c3n2)cc1O Show InChI InChI=1S/C24H15F2NO4/c25-18-9-5-15(12-19(18)26)23(30)17-8-4-14-3-7-16(27-22(14)24(17)31)6-1-13-2-10-20(28)21(29)11-13/h1-12,28-29,31H/b6-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Unité Associée au CNRS Curated by ChEMBL					Assay Description In vitro inhibitory concentration against HIV-1 recombinant integrase activity in strand transfer assay				Bioorg Med Chem Lett 15: 4019-22 (2005) Article DOI: 10.1016/j.bmcl.2005.06.036 BindingDB Entry DOI: 10.7270/Q2GM86VW
					More data for this Ligand-Target Pair