BDBM50170283 CHEMBL3805292

SMILES: Cn1nccc1-c1csc(c1)C(=O)NC1(CCNCC1)c1ccc(F)cc1

InChI Key: InChIKey=NAIQKXKDKHEYMA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50170283   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50170283 (CHEMBL3805292) Show SMILES Cn1nccc1-c1csc(c1)C(=O)NC1(CCNCC1)c1ccc(F)cc1 Show InChI InChI=1S/C20H21FN4OS/c1-25-17(6-9-23-25)14-12-18(27-13-14)19(26)24-20(7-10-22-11-8-20)15-2-4-16(21)5-3-15/h2-6,9,12-13,22H,7-8,10-11H2,1H3,(H,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	920	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of Akt1 (unknown origin) expressed in Escherichia coli using peptide substrate after 1 hr by HTRF assay				Eur J Med Chem 117: 47-58 (2016) BindingDB Entry DOI: 10.7270/Q2QJ7K5K
					More data for this Ligand-Target Pair