BDBM50170295 (S)-2-{4'-[(Benzofuran-2-carbonyl)-amino]-biphenyl-4-sulfonylamino}-succinamic acid::CHEMBL188542

SMILES: NC(=O)C[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(NC(=O)c2cc3ccccc3o2)cc1)C(O)=O

InChI Key: InChIKey=KJURPZKHCXAZLJ-FQEVSTJZSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50170295   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase 13 (Bos taurus)	BDBM50170295 ((S)-2-{4'-[(Benzofuran-2-carbonyl)-amino]-biphenyl...) Show SMILES NC(=O)C[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(NC(=O)c2cc3ccccc3o2)cc1)C(O)=O Show InChI InChI=1S/C25H21N3O7S/c26-23(29)14-20(25(31)32)28-36(33,34)19-11-7-16(8-12-19)15-5-9-18(10-6-15)27-24(30)22-13-17-3-1-2-4-21(17)35-22/h1-13,20,28H,14H2,(H2,26,29)(H,27,30)(H,31,32)/t20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against MMP-13 of bovine articular cartilage explants				Bioorg Med Chem Lett 15: 4105-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.019 BindingDB Entry DOI: 10.7270/Q2TX3DXK
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50170295 ((S)-2-{4'-[(Benzofuran-2-carbonyl)-amino]-biphenyl...) Show SMILES NC(=O)C[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(NC(=O)c2cc3ccccc3o2)cc1)C(O)=O Show InChI InChI=1S/C25H21N3O7S/c26-23(29)14-20(25(31)32)28-36(33,34)19-11-7-16(8-12-19)15-5-9-18(10-6-15)27-24(30)22-13-17-3-1-2-4-21(17)35-22/h1-13,20,28H,14H2,(H2,26,29)(H,27,30)(H,31,32)/t20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against MMP-2				Bioorg Med Chem Lett 15: 4105-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.019 BindingDB Entry DOI: 10.7270/Q2TX3DXK
					More data for this Ligand-Target Pair