BDBM50170382 5-(2-Methoxy-2-phenyl-ethyl)-thiazole-4-carboxylic acid thiazol-2-ylamide::CHEMBL365192

SMILES: COC(Cc1scnc1C(=O)Nc1nccs1)c1ccccc1

InChI Key: InChIKey=GOKCUAGZJCANPH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50170382   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50170382 (5-(2-Methoxy-2-phenyl-ethyl)-thiazole-4-carboxylic...) Show SMILES COC(Cc1scnc1C(=O)Nc1nccs1)c1ccccc1 Show InChI InChI=1S/C16H15N3O2S2/c1-21-12(11-5-3-2-4-6-11)9-13-14(18-10-23-13)15(20)19-16-17-7-8-22-16/h2-8,10,12H,9H2,1H3,(H,17,19,20)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration against EcMetAP1 enzyme activity				Bioorg Med Chem Lett 15: 4130-5 (2005) Article DOI: 10.1016/j.bmcl.2005.06.005 BindingDB Entry DOI: 10.7270/Q2FN15RH
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Saccharomyces cerevisiae)	BDBM50170382 (5-(2-Methoxy-2-phenyl-ethyl)-thiazole-4-carboxylic...) Show SMILES COC(Cc1scnc1C(=O)Nc1nccs1)c1ccccc1 Show InChI InChI=1S/C16H15N3O2S2/c1-21-12(11-5-3-2-4-6-11)9-13-14(18-10-23-13)15(20)19-16-17-7-8-22-16/h2-8,10,12H,9H2,1H3,(H,17,19,20)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration against ScMetAP1 enzyme activity				Bioorg Med Chem Lett 15: 4130-5 (2005) Article DOI: 10.1016/j.bmcl.2005.06.005 BindingDB Entry DOI: 10.7270/Q2FN15RH
					More data for this Ligand-Target Pair