BDBM50170412 CHEMBL179345::N-[4-(3-Dimethylamino-pyrrolidin-1-yl)-phenyl]-6-phenyl-nicotinamide

SMILES: CN(C)C1CCN(C1)c1ccc(NC(=O)c2ccc(nc2)-c2ccccc2)cc1

InChI Key: InChIKey=RMUJYXNEWDVEQS-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50170412   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50170412 (CHEMBL179345 | N-[4-(3-Dimethylamino-pyrrolidin-1-...) Show SMILES CN(C)C1CCN(C1)c1ccc(NC(=O)c2ccc(nc2)-c2ccccc2)cc1 Show InChI InChI=1S/C24H26N4O/c1-27(2)22-14-15-28(17-22)21-11-9-20(10-12-21)26-24(29)19-8-13-23(25-16-19)18-6-4-3-5-7-18/h3-13,16,22H,14-15,17H2,1-2H3,(H,26,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human MCH-R1 evaluated by its ability to displace radioligand [125I]-Tyr13]-MCH				Bioorg Med Chem Lett 15: 3701-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.130 BindingDB Entry DOI: 10.7270/Q29W0F16
					More data for this Ligand-Target Pair