BDBM50170463 (R)-1-(4-Fluoro-phenyl)-piperazine-2-carboxylic acid {(R)-3-[6-(4-chloro-phenylsulfanyl)-2-(4-methoxy-phenyl)-3-oxo-2,3-dihydro-pyridazin-4-yl]-1-methyl-propyl}-amide::CHEMBL362314

SMILES: COc1ccc(cc1)-n1nc(Sc2ccc(Cl)cc2)cc(CC[C@@H](C)NC(=O)[C@H]2CNCCN2c2ccc(F)cc2)c1=O

InChI Key: InChIKey=HZMVJLWFSIUIPU-ONOMSOESSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50170463   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50170463 ((R)-1-(4-Fluoro-phenyl)-piperazine-2-carboxylic ac...) Show SMILES COc1ccc(cc1)-n1nc(Sc2ccc(Cl)cc2)cc(CC[C@@H](C)NC(=O)[C@H]2CNCCN2c2ccc(F)cc2)c1=O Show InChI InChI=1S/C32H33ClFN5O3S/c1-21(36-31(40)29-20-35-17-18-38(29)25-9-7-24(34)8-10-25)3-4-22-19-30(43-28-15-5-23(33)6-16-28)37-39(32(22)41)26-11-13-27(42-2)14-12-26/h5-16,19,21,29,35H,3-4,17-18,20H2,1-2H3,(H,36,40)/t21-,29-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration at human melanocortin 4 receptor in cAMP release assay				Bioorg Med Chem Lett 15: 4023-8 (2005) Article DOI: 10.1016/j.bmcl.2005.06.033 BindingDB Entry DOI: 10.7270/Q2639P8S
					More data for this Ligand-Target Pair