BDBM50170473 6-Phenoxymethyl-pyridine-2-carboxylic acid (4-hydroxycarbamoylmethyl-5-methyl-thiazol-2-yl)-amide::CHEMBL190849

SMILES: Cc1sc(NC(=O)c2cccc(COc3ccccc3)n2)nc1CC(=O)NO

InChI Key: InChIKey=IFMVPLWFKLYRDU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50170473   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50170473 (6-Phenoxymethyl-pyridine-2-carboxylic acid (4-hydr...) Show SMILES Cc1sc(NC(=O)c2cccc(COc3ccccc3)n2)nc1CC(=O)NO Show InChI InChI=1S/C19H18N4O4S/c1-12-16(10-17(24)23-26)21-19(28-12)22-18(25)15-9-5-6-13(20-15)11-27-14-7-3-2-4-8-14/h2-9,26H,10-11H2,1H3,(H,23,24)(H,21,22,25)	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibitory concentration against Phosphodiesterase type 5				Bioorg Med Chem Lett 15: 4085-90 (2005) Article DOI: 10.1016/j.bmcl.2005.06.016 BindingDB Entry DOI: 10.7270/Q22B8XKH
					More data for this Ligand-Target Pair
Phosphodiesterase 1 (Homo sapiens (Human))	BDBM50170473 (6-Phenoxymethyl-pyridine-2-carboxylic acid (4-hydr...) Show SMILES Cc1sc(NC(=O)c2cccc(COc3ccccc3)n2)nc1CC(=O)NO Show InChI InChI=1S/C19H18N4O4S/c1-12-16(10-17(24)23-26)21-19(28-12)22-18(25)15-9-5-6-13(20-15)11-27-14-7-3-2-4-8-14/h2-9,26H,10-11H2,1H3,(H,23,24)(H,21,22,25)	PDB MMDB KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibitory concentration against Phosphodiesterase type 1				Bioorg Med Chem Lett 15: 4085-90 (2005) Article DOI: 10.1016/j.bmcl.2005.06.016 BindingDB Entry DOI: 10.7270/Q22B8XKH
					More data for this Ligand-Target Pair