BDBM50170571 (3-Amino-benzo[b]thiophen-2-yl)-(3,4,5-trimethoxy-phenyl)-methanone::2-(3,4,5-trimethoxybenzoyl)-3-aminobenzo[b]thiophene::CHEMBL371795

SMILES: COc1cc(cc(OC)c1OC)C(=O)c1sc2ccccc2c1N

InChI Key: InChIKey=FXEBQYJUWASDMF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50170571   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta tubulin (Leishmania donovani)	BDBM50170571 ((3-Amino-benzo[b]thiophen-2-yl)-(3,4,5-trimethoxy-...) Show SMILES COc1cc(cc(OC)c1OC)C(=O)c1sc2ccccc2c1N Show InChI InChI=1S/C18H17NO4S/c1-21-12-8-10(9-13(22-2)17(12)23-3)16(20)18-15(19)11-6-4-5-7-14(11)24-18/h4-9H,19H2,1-3H3	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universitá di Ferrara Curated by ChEMBL					Assay Description Concentration required to inhibit tubulin polymerization at 10 uM				Bioorg Med Chem Lett 15: 4048-52 (2005) Article DOI: 10.1016/j.bmcl.2005.06.022 BindingDB Entry DOI: 10.7270/Q2XP74GG
					More data for this Ligand-Target Pair