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SMILES: CN1CCC[C@H]1COc1cnc(Cl)c(c1)-c1ccc(Cl)cc1

InChI Key: InChIKey=XEKZEACGPKAUFE-AWEZNQCLSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50170595   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-7


(Homo sapiens (Human))		BDBM50170595
PNG
(2-Chloro-3-(4-chloro-phenyl)-5-((S)-1-methyl-pyrro...)
Show SMILES CN1CCC[C@H]1COc1cnc(Cl)c(c1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C17H18Cl2N2O/c1-21-8-2-3-14(21)11-22-15-9-16(17(19)20-10-15)12-4-6-13(18)7-5-12/h4-7,9-10,14H,2-3,8,11H2,1H3/t14-/m0/s1
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Article
PubMed
n/an/a 8.50E+3n/an/an/an/an/an/a



The Danish University of Pharmaceutical Sciences

Curated by ChEMBL


Assay Description
Inhibitory concentration against Nicotinic acetylcholine receptor alpha 7

J Med Chem 48: 4705-45 (2005)


Article DOI: 10.1021/jm040219e
BindingDB Entry DOI: 10.7270/Q29W0G79
More data for this
Ligand-Target Pair