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SMILES: O=C([C@H](Cc1ccccc1)NC(=O)c1cccc(c1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCCC1)N1CCCC1

InChI Key: InChIKey=DKNQJIJHKLVBSI-KYJUHHDHSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50170694   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prolyl endopeptidase


(Sus scrofa)		BDBM50170694
PNG
(CHEMBL362737 | N,N'-Bis-((S)-1-benzyl-2-oxo-2-pyrr...)
Show SMILES O=C([C@H](Cc1ccccc1)NC(=O)c1cccc(c1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCCC1)N1CCCC1
Show InChI InChI=1S/C34H38N4O4/c39-31(35-29(22-25-12-3-1-4-13-25)33(41)37-18-7-8-19-37)27-16-11-17-28(24-27)32(40)36-30(23-26-14-5-2-6-15-26)34(42)38-20-9-10-21-38/h1-6,11-17,24,29-30H,7-10,18-23H2,(H,35,39)(H,36,40)/t29-,30-/m0/s1
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Similars
Article
PubMed
n/an/a 81n/an/an/an/a7.0n/a



University of Kuopio

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against porcine prolyl oligopeptidase by using 4 mM Suc-Gly-Pro-7-amido-4-methylcoumarin as substrate (pH 7.0) at 30 deg...

J Med Chem 48: 4772-82 (2005)


Article DOI: 10.1021/jm0500020
BindingDB Entry DOI: 10.7270/Q22B8ZT2
More data for this
Ligand-Target Pair