BDBM50170719 2-Amino-propionic acid 2-amino-4-oxo-3,4,5,6,7,8-hexahydro-pteridin-6-ylmethyl ester::CHEMBL359988

SMILES: CC(N)C(=O)OCC1CNc2nc(N)[nH]c(=O)c2N1

InChI Key: InChIKey=AECPLDIAUVDACN-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50170719   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric oxide synthase, brain (Homo sapiens (Human))	BDBM50170719 (2-Amino-propionic acid 2-amino-4-oxo-3,4,5,6,7,8-h...) Show SMILES CC(N)C(=O)OCC1CNc2nc(N)[nH]c(=O)c2N1 Show InChI InChI=1S/C10H16N6O3/c1-4(11)9(18)19-3-5-2-13-7-6(14-5)8(17)16-10(12)15-7/h4-5,14H,2-3,11H2,1H3,(H4,12,13,15,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.17E+5	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Curated by ChEMBL					Assay Description Inhibitory activity against human Nitric oxide synthase-I with 2 uM H4Bip for 30 min				J Med Chem 48: 4783-92 (2005) Article DOI: 10.1021/jm050007x BindingDB Entry DOI: 10.7270/Q28W3CTH
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50170719 (2-Amino-propionic acid 2-amino-4-oxo-3,4,5,6,7,8-h...) Show SMILES CC(N)C(=O)OCC1CNc2nc(N)[nH]c(=O)c2N1 Show InChI InChI=1S/C10H16N6O3/c1-4(11)9(18)19-3-5-2-13-7-6(14-5)8(17)16-10(12)15-7/h4-5,14H,2-3,11H2,1H3,(H4,12,13,15,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Curated by ChEMBL					Assay Description Inhibitory activity against human Nitric oxide synthase-II with 2 uM H4Bip for 30 min				J Med Chem 48: 4783-92 (2005) Article DOI: 10.1021/jm050007x BindingDB Entry DOI: 10.7270/Q28W3CTH
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Homo sapiens (Human))	BDBM50170719 (2-Amino-propionic acid 2-amino-4-oxo-3,4,5,6,7,8-h...) Show SMILES CC(N)C(=O)OCC1CNc2nc(N)[nH]c(=O)c2N1 Show InChI InChI=1S/C10H16N6O3/c1-4(11)9(18)19-3-5-2-13-7-6(14-5)8(17)16-10(12)15-7/h4-5,14H,2-3,11H2,1H3,(H4,12,13,15,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Curated by ChEMBL					Assay Description Inhibitory activity against human Nitric oxide synthase-III with 2 uM H4Bip for 30 min				J Med Chem 48: 4783-92 (2005) Article DOI: 10.1021/jm050007x BindingDB Entry DOI: 10.7270/Q28W3CTH
					More data for this Ligand-Target Pair