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BDBM50170894 CHEMBL3805338

SMILES: NC(CNCC1CCNCC1)P(O)(O)=O

InChI Key: InChIKey=URLVWQSQTPWELN-UHFFFAOYNA-N

Data: 5 KI

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50170894   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Endoplasmic reticulum aminopeptidase 2


(Homo sapiens)
BDBM50170894
PNG
(CHEMBL3805338)
Show SMILES NC(CNCC1CCNCC1)P(O)(O)=O
Show InChI InChI=1/C8H20N3O3P/c9-8(15(12,13)14)6-11-5-7-1-3-10-4-2-7/h7-8,10-11H,1-6,9H2,(H2,12,13,14)
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Article
PubMed
1.42E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of human ERAP2 preincubated for 30 to 60 mins followed by addition of Arg-AMC as substrate measured for 15 mins by spectrofluorimetric met...


Bioorg Med Chem Lett 26: 4122-6 (2016)

More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens)
BDBM50170894
PNG
(CHEMBL3805338)
Show SMILES NC(CNCC1CCNCC1)P(O)(O)=O
Show InChI InChI=1/C8H20N3O3P/c9-8(15(12,13)14)6-11-5-7-1-3-10-4-2-7/h7-8,10-11H,1-6,9H2,(H2,12,13,14)
PDB

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PubMed
3.29E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea...


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50170894
PNG
(CHEMBL3805338)
Show SMILES NC(CNCC1CCNCC1)P(O)(O)=O
Show InChI InChI=1/C8H20N3O3P/c9-8(15(12,13)14)6-11-5-7-1-3-10-4-2-7/h7-8,10-11H,1-6,9H2,(H2,12,13,14)
PDB

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PubMed
9.39E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition measured f...


Citation and Details
More data for this
Ligand-Target Pair
Leucine aminopeptidase (LAP)


(Sus scrofa (Pig))
BDBM50170894
PNG
(CHEMBL3805338)
Show SMILES NC(CNCC1CCNCC1)P(O)(O)=O
Show InChI InChI=1/C8H20N3O3P/c9-8(15(12,13)14)6-11-5-7-1-3-10-4-2-7/h7-8,10-11H,1-6,9H2,(H2,12,13,14)
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UniChem

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PubMed
6.84E+4n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney leucine aminopeptidase M17 using Leu-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition meas...


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase


(Homo sapiens)
BDBM50170894
PNG
(CHEMBL3805338)
Show SMILES NC(CNCC1CCNCC1)P(O)(O)=O
Show InChI InChI=1/C8H20N3O3P/c9-8(15(12,13)14)6-11-5-7-1-3-10-4-2-7/h7-8,10-11H,1-6,9H2,(H2,12,13,14)
PDB
MMDB

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antibodypedia
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Article
PubMed
>2.50E+5n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of human ERAP1 preincubated for 30 to 60 mins followed by addition of Leu-AMC as substrate measured for 15 mins by spectrofluorimetric met...


Bioorg Med Chem Lett 26: 4122-6 (2016)

More data for this
Ligand-Target Pair