BDBM50170946 2-(4-Methoxy-phenyl)-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-one::CHEMBL363150

SMILES: COc1ccc(cc1)-n1cc2c(n1)c1ccccc1[nH]c2=O

InChI Key: InChIKey=CNHTZPNBXUMLLT-UHFFFAOYSA-N

Data: 4 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50170946   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50170946 (2-(4-Methoxy-phenyl)-2,5-dihydro-pyrazolo[4,3-c]qu...) Show SMILES COc1ccc(cc1)-n1cc2c(n1)c1ccccc1[nH]c2=O Show InChI InChI=1S/C17H13N3O2/c1-22-12-8-6-11(7-9-12)20-10-14-16(19-20)13-4-2-3-5-15(13)18-17(14)21/h2-10H,1H3,(H,18,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Ferrara Curated by ChEMBL					Assay Description Inhibition of [3H]-MRE3008-F20 binding to human adenosine A3 receptor expressed in CHO cells; (n=3 - 6)				J Med Chem 48: 5001-8 (2005) Article DOI: 10.1021/jm050125k BindingDB Entry DOI: 10.7270/Q24749DW
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50170946 (2-(4-Methoxy-phenyl)-2,5-dihydro-pyrazolo[4,3-c]qu...) Show SMILES COc1ccc(cc1)-n1cc2c(n1)c1ccccc1[nH]c2=O Show InChI InChI=1S/C17H13N3O2/c1-22-12-8-6-11(7-9-12)20-10-14-16(19-20)13-4-2-3-5-15(13)18-17(14)21/h2-10H,1H3,(H,18,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Ferrara Curated by ChEMBL					Assay Description Inhibition of cAMP accumulation in human adenosine A3 receptor assay as inhibition of Cl-IB-MECA				J Med Chem 48: 5001-8 (2005) Article DOI: 10.1021/jm050125k BindingDB Entry DOI: 10.7270/Q24749DW
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50170946 (2-(4-Methoxy-phenyl)-2,5-dihydro-pyrazolo[4,3-c]qu...) Show SMILES COc1ccc(cc1)-n1cc2c(n1)c1ccccc1[nH]c2=O Show InChI InChI=1S/C17H13N3O2/c1-22-12-8-6-11(7-9-12)20-10-14-16(19-20)13-4-2-3-5-15(13)18-17(14)21/h2-10H,1H3,(H,18,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Ferrara Curated by ChEMBL					Assay Description Inhibition of [3H]-DPCPX binding to human adenosine A1 receptor expressed in CHO cells; (n=3 - 6)				J Med Chem 48: 5001-8 (2005) Article DOI: 10.1021/jm050125k BindingDB Entry DOI: 10.7270/Q24749DW
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50170946 (2-(4-Methoxy-phenyl)-2,5-dihydro-pyrazolo[4,3-c]qu...) Show SMILES COc1ccc(cc1)-n1cc2c(n1)c1ccccc1[nH]c2=O Show InChI InChI=1S/C17H13N3O2/c1-22-12-8-6-11(7-9-12)20-10-14-16(19-20)13-4-2-3-5-15(13)18-17(14)21/h2-10H,1H3,(H,18,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Ferrara Curated by ChEMBL					Assay Description Inhibition of [3H]-ZM-241,385 binding to human adenosine A2a receptor expressed in CHO cells; (n=3 - 6)				J Med Chem 48: 5001-8 (2005) Article DOI: 10.1021/jm050125k BindingDB Entry DOI: 10.7270/Q24749DW
					More data for this Ligand-Target Pair
Adenosine receptor A2b (Homo sapiens (Human))	BDBM50170946 (2-(4-Methoxy-phenyl)-2,5-dihydro-pyrazolo[4,3-c]qu...) Show SMILES COc1ccc(cc1)-n1cc2c(n1)c1ccccc1[nH]c2=O Show InChI InChI=1S/C17H13N3O2/c1-22-12-8-6-11(7-9-12)20-10-14-16(19-20)13-4-2-3-5-15(13)18-17(14)21/h2-10H,1H3,(H,18,21)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Ferrara Curated by ChEMBL					Assay Description Inhibition of 100 nM-NECA stimulation of cAMP levels in human adenosine A2b receptor expressing CHO cells				J Med Chem 48: 5001-8 (2005) Article DOI: 10.1021/jm050125k BindingDB Entry DOI: 10.7270/Q24749DW
					More data for this Ligand-Target Pair