BDBM50170947 2-Phenyl-2,5-dihydro-pyrazolo[4,3-c]quinoline-4-thione::CHEMBL187842

SMILES: S=c1[nH]c2ccccc2c2nn(cc12)-c1ccccc1

InChI Key: InChIKey=GPZDEXVCMNVCGO-UHFFFAOYSA-N

Data: 3 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50170947   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50170947 (2-Phenyl-2,5-dihydro-pyrazolo[4,3-c]quinoline-4-th...) Show SMILES S=c1[nH]c2ccccc2c2nn(cc12)-c1ccccc1 Show InChI InChI=1S/C16H11N3S/c20-16-13-10-19(11-6-2-1-3-7-11)18-15(13)12-8-4-5-9-14(12)17-16/h1-10H,(H,17,20)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Ferrara Curated by ChEMBL					Assay Description Inhibition of [3H]-MRE3008-F20 binding to human adenosine A3 receptor expressed in CHO cells; (n=3 - 6)				J Med Chem 48: 5001-8 (2005) Article DOI: 10.1021/jm050125k BindingDB Entry DOI: 10.7270/Q24749DW
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50170947 (2-Phenyl-2,5-dihydro-pyrazolo[4,3-c]quinoline-4-th...) Show SMILES S=c1[nH]c2ccccc2c2nn(cc12)-c1ccccc1 Show InChI InChI=1S/C16H11N3S/c20-16-13-10-19(11-6-2-1-3-7-11)18-15(13)12-8-4-5-9-14(12)17-16/h1-10H,(H,17,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Ferrara Curated by ChEMBL					Assay Description Inhibition of [3H]-DPCPX binding to human adenosine A1 receptor expressed in CHO cells; (n=3 - 6)				J Med Chem 48: 5001-8 (2005) Article DOI: 10.1021/jm050125k BindingDB Entry DOI: 10.7270/Q24749DW
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50170947 (2-Phenyl-2,5-dihydro-pyrazolo[4,3-c]quinoline-4-th...) Show SMILES S=c1[nH]c2ccccc2c2nn(cc12)-c1ccccc1 Show InChI InChI=1S/C16H11N3S/c20-16-13-10-19(11-6-2-1-3-7-11)18-15(13)12-8-4-5-9-14(12)17-16/h1-10H,(H,17,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Ferrara Curated by ChEMBL					Assay Description Inhibition of [3H]-ZM-241,385 binding to human adenosine A2a receptor expressed in CHO cells; (n=3 - 6)				J Med Chem 48: 5001-8 (2005) Article DOI: 10.1021/jm050125k BindingDB Entry DOI: 10.7270/Q24749DW
					More data for this Ligand-Target Pair
Adenosine receptor A2b (Homo sapiens (Human))	BDBM50170947 (2-Phenyl-2,5-dihydro-pyrazolo[4,3-c]quinoline-4-th...) Show SMILES S=c1[nH]c2ccccc2c2nn(cc12)-c1ccccc1 Show InChI InChI=1S/C16H11N3S/c20-16-13-10-19(11-6-2-1-3-7-11)18-15(13)12-8-4-5-9-14(12)17-16/h1-10H,(H,17,20)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Ferrara Curated by ChEMBL					Assay Description Inhibition of 100 nM-NECA stimulation of cAMP levels in human adenosine A2b receptor expressing CHO cells				J Med Chem 48: 5001-8 (2005) Article DOI: 10.1021/jm050125k BindingDB Entry DOI: 10.7270/Q24749DW
					More data for this Ligand-Target Pair