BDBM50170950 4-Methoxy-2-phenyl-2H-pyrazolo[4,3-c]quinoline::CHEMBL188052

SMILES: COc1nc2ccccc2c2nn(cc12)-c1ccccc1

InChI Key: InChIKey=LBRDTSFKAURCRO-UHFFFAOYSA-N

Data: 3 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50170950   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50170950 (4-Methoxy-2-phenyl-2H-pyrazolo[4,3-c]quinoline | C...) Show SMILES COc1nc2ccccc2c2nn(cc12)-c1ccccc1 Show InChI InChI=1S/C17H13N3O/c1-21-17-14-11-20(12-7-3-2-4-8-12)19-16(14)13-9-5-6-10-15(13)18-17/h2-11H,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	166	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Ferrara Curated by ChEMBL					Assay Description Inhibition of [3H]-MRE3008-F20 binding to human adenosine A3 receptor expressed in CHO cells; (n=3 - 6)				J Med Chem 48: 5001-8 (2005) Article DOI: 10.1021/jm050125k BindingDB Entry DOI: 10.7270/Q24749DW
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50170950 (4-Methoxy-2-phenyl-2H-pyrazolo[4,3-c]quinoline | C...) Show SMILES COc1nc2ccccc2c2nn(cc12)-c1ccccc1 Show InChI InChI=1S/C17H13N3O/c1-21-17-14-11-20(12-7-3-2-4-8-12)19-16(14)13-9-5-6-10-15(13)18-17/h2-11H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Ferrara Curated by ChEMBL					Assay Description Inhibition of [3H]-ZM-241,385 binding to human adenosine A2a receptor expressed in CHO cells; (n=3 - 6)				J Med Chem 48: 5001-8 (2005) Article DOI: 10.1021/jm050125k BindingDB Entry DOI: 10.7270/Q24749DW
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50170950 (4-Methoxy-2-phenyl-2H-pyrazolo[4,3-c]quinoline | C...) Show SMILES COc1nc2ccccc2c2nn(cc12)-c1ccccc1 Show InChI InChI=1S/C17H13N3O/c1-21-17-14-11-20(12-7-3-2-4-8-12)19-16(14)13-9-5-6-10-15(13)18-17/h2-11H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Ferrara Curated by ChEMBL					Assay Description Inhibition of [3H]-DPCPX binding to human adenosine A1 receptor expressed in CHO cells; (n=3 - 6)				J Med Chem 48: 5001-8 (2005) Article DOI: 10.1021/jm050125k BindingDB Entry DOI: 10.7270/Q24749DW
					More data for this Ligand-Target Pair
Adenosine receptor A2b (Homo sapiens (Human))	BDBM50170950 (4-Methoxy-2-phenyl-2H-pyrazolo[4,3-c]quinoline | C...) Show SMILES COc1nc2ccccc2c2nn(cc12)-c1ccccc1 Show InChI InChI=1S/C17H13N3O/c1-21-17-14-11-20(12-7-3-2-4-8-12)19-16(14)13-9-5-6-10-15(13)18-17/h2-11H,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Ferrara Curated by ChEMBL					Assay Description Inhibition of 100 nM-NECA stimulation of cAMP levels in human adenosine A2b receptor expressing CHO cells				J Med Chem 48: 5001-8 (2005) Article DOI: 10.1021/jm050125k BindingDB Entry DOI: 10.7270/Q24749DW
					More data for this Ligand-Target Pair