BDBM50171031 CHEMBL3804977

SMILES: Cc1nc2cc(Cl)cc(Cl)c2cc1C1=CCCCC1

InChI Key: InChIKey=PIJQLZPDQBVATL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50171031   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
20S proteasome chymotrypsin-like (Homo sapiens (Human))	BDBM50171031 (CHEMBL3804977) Show SMILES Cc1nc2cc(Cl)cc(Cl)c2cc1C1=CCCCC1 |t:15| Show InChI InChI=1S/C16H15Cl2N/c1-10-13(11-5-3-2-4-6-11)9-14-15(18)7-12(17)8-16(14)19-10/h5,7-9H,2-4,6H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair