BDBM50171036 CHEMBL3805729

SMILES: Cc1cc(C)c2cc(cnc2c1)C1=CCCCC1

InChI Key: InChIKey=YUVBJPXYQYFHIM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50171036   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
20S proteasome chymotrypsin-like (Homo sapiens (Human))	BDBM50171036 (CHEMBL3805729) Show SMILES Cc1cc(C)c2cc(cnc2c1)C1=CCCCC1 |t:14| Show InChI InChI=1S/C17H19N/c1-12-8-13(2)16-10-15(11-18-17(16)9-12)14-6-4-3-5-7-14/h6,8-11H,3-5,7H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.38E+4	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair