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SMILES: CCc1cc2cc(ccc2nc1CC)N(C)C

InChI Key: InChIKey=SVKMRJSVMOCUME-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50171079   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proteasome subunit beta type-5


(Homo sapiens (Human))		BDBM50171079
PNG
(CHEMBL3805403)
Show SMILES CCc1cc2cc(ccc2nc1CC)N(C)C
Show InChI InChI=1S/C15H20N2/c1-5-11-9-12-10-13(17(3)4)7-8-15(12)16-14(11)6-2/h7-10H,5-6H2,1-4H3
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MMDB

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PubMed
n/an/a 1.87E+4n/an/an/an/an/an/a



Michigan State University

Curated by ChEMBL


Assay Description
Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay

Bioorg Med Chem 24: 2441-50 (2016)


BindingDB Entry DOI: 10.7270/Q2PK0J26
More data for this
Ligand-Target Pair