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SMILES: OC(=O)COc1ccc(cc1)C(=O)N(Cc1ccc(cc1)-c1csnn1)Cc1ccc(cc1)C(F)(F)P(O)(O)=O

InChI Key: InChIKey=GMALMXCDHHXTFM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50171121   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM50171121
PNG
(CHEMBL197827 | {4-[[4-(Difluoro-phosphono-methyl)-...)
Show SMILES OC(=O)COc1ccc(cc1)C(=O)N(Cc1ccc(cc1)-c1csnn1)Cc1ccc(cc1)C(F)(F)P(O)(O)=O
Show InChI InChI=1S/C26H22F2N3O7PS/c27-26(28,39(35,36)37)21-9-3-18(4-10-21)14-31(13-17-1-5-19(6-2-17)23-16-40-30-29-23)25(34)20-7-11-22(12-8-20)38-15-24(32)33/h1-12,16H,13-15H2,(H,32,33)(H2,35,36,37)
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Article
PubMed
n/an/a 2.30E+3n/an/an/an/an/an/a



Affymax, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against protein tyrosine phosphatase 1B using O-methyl fluorescein monophosphate

Bioorg Med Chem Lett 15: 4336-41 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.061
BindingDB Entry DOI: 10.7270/Q2M61JSK
More data for this
Ligand-Target Pair