BDBM50171428 5-Thiophen-2-yl-3-p-tolyl-[1,2,4]oxadiazole::CHEMBL191015::cid_784811

SMILES: Cc1ccc(cc1)-c1noc(n1)-c1cccs1

InChI Key: InChIKey=ZBIZYSIIJRBDSE-UHFFFAOYSA-N

Data: 2 IC50  6 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50171428   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear factor NF-kappa-B (Homo sapiens (Human))	BDBM50171428 (5-Thiophen-2-yl-3-p-tolyl-[1,2,4]oxadiazole | CHEM...) Show SMILES Cc1ccc(cc1)-c1noc(n1)-c1cccs1 Show InChI InChI=1S/C13H10N2OS/c1-9-4-6-10(7-5-9)12-14-13(16-15-12)11-3-2-8-17-11/h2-8H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	n/a	n/a	2.29E+3	n/a	n/a	n/a	n/a
SRMLSC Curated by PubChem BioAssay					Assay Description Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q27P8WT7
					More data for this Ligand-Target Pair
SKiNhead family member (skn-1) (Caenorhabditis elegans)	BDBM50171428 (5-Thiophen-2-yl-3-p-tolyl-[1,2,4]oxadiazole | CHEM...) Show SMILES Cc1ccc(cc1)-c1noc(n1)-c1cccs1 Show InChI InChI=1S/C13H10N2OS/c1-9-4-6-10(7-5-9)12-14-13(16-15-12)11-3-2-8-17-11/h2-8H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	1.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay									PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2DV1HH8
					More data for this Ligand-Target Pair
Protein HSP-16.2 (Caenorhabditis elegans)	BDBM50171428 (5-Thiophen-2-yl-3-p-tolyl-[1,2,4]oxadiazole | CHEM...) Show SMILES Cc1ccc(cc1)-c1noc(n1)-c1cccs1 Show InChI InChI=1S/C13H10N2OS/c1-9-4-6-10(7-5-9)12-14-13(16-15-12)11-3-2-8-17-11/h2-8H,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	>6.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay									PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q21J98BN
					More data for this Ligand-Target Pair
Caspase-3 (Homo sapiens (Human))	BDBM50171428 (5-Thiophen-2-yl-3-p-tolyl-[1,2,4]oxadiazole | CHEM...) Show SMILES Cc1ccc(cc1)-c1noc(n1)-c1cccs1 Show InChI InChI=1S/C13H10N2OS/c1-9-4-6-10(7-5-9)12-14-13(16-15-12)11-3-2-8-17-11/h2-8H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Maxim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Caspase-3 activation activity tested in DLD1 colon cells done for 24 or 48 h at 37 degree C				J Med Chem 48: 5215-23 (2005) Article DOI: 10.1021/jm050292k BindingDB Entry DOI: 10.7270/Q2XG9QNF
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50171428 (5-Thiophen-2-yl-3-p-tolyl-[1,2,4]oxadiazole | CHEM...) Show SMILES Cc1ccc(cc1)-c1noc(n1)-c1cccs1 Show InChI InChI=1S/C13H10N2OS/c1-9-4-6-10(7-5-9)12-14-13(16-15-12)11-3-2-8-17-11/h2-8H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	n/a	n/a	6.75E+4	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...				PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q23F4N80
					More data for this Ligand-Target Pair
Caspase-3 (Homo sapiens (Human))	BDBM50171428 (5-Thiophen-2-yl-3-p-tolyl-[1,2,4]oxadiazole | CHEM...) Show SMILES Cc1ccc(cc1)-c1noc(n1)-c1cccs1 Show InChI InChI=1S/C13H10N2OS/c1-9-4-6-10(7-5-9)12-14-13(16-15-12)11-3-2-8-17-11/h2-8H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a
Maxim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Caspase-3 activation activity tested in H1299 lung cancer cells done for 24 or 48 h at 37 degree C				J Med Chem 48: 5215-23 (2005) Article DOI: 10.1021/jm050292k BindingDB Entry DOI: 10.7270/Q2XG9QNF
					More data for this Ligand-Target Pair
Caspase-3 (Homo sapiens (Human))	BDBM50171428 (5-Thiophen-2-yl-3-p-tolyl-[1,2,4]oxadiazole | CHEM...) Show SMILES Cc1ccc(cc1)-c1noc(n1)-c1cccs1 Show InChI InChI=1S/C13H10N2OS/c1-9-4-6-10(7-5-9)12-14-13(16-15-12)11-3-2-8-17-11/h2-8H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a
Maxim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Caspase-3 activation activity tested in T47D breast cells done for 24 or 48 h at 37 degree C				J Med Chem 48: 5215-23 (2005) Article DOI: 10.1021/jm050292k BindingDB Entry DOI: 10.7270/Q2XG9QNF
					More data for this Ligand-Target Pair
Protein DAF-12, isoform a (Caenorhabditis elegans)	BDBM50171428 (5-Thiophen-2-yl-3-p-tolyl-[1,2,4]oxadiazole | CHEM...) Show SMILES Cc1ccc(cc1)-c1noc(n1)-c1cccs1 Show InChI InChI=1S/C13H10N2OS/c1-9-4-6-10(7-5-9)12-14-13(16-15-12)11-3-2-8-17-11/h2-8H,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	n/a	n/a	6.75E+4	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2BV7F8Z
					More data for this Ligand-Target Pair