BDBM50171600 CHEMBL371700::N-(1-Benzo[1,3]dioxol-5-ylmethyl-piperidin-4-yl)-5-chloro-2-[(1H-imidazol-4-ylmethyl)-amino]-nicotinamide

SMILES: Clc1cnc(NCc2cnc[nH]2)c(c1)C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1

InChI Key: InChIKey=FHPVJZFHHRUENR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50171600   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50171600 (CHEMBL371700 | N-(1-Benzo[1,3]dioxol-5-ylmethyl-pi...) Show SMILES Clc1cnc(NCc2cnc[nH]2)c(c1)C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1 Show InChI InChI=1S/C23H25ClN6O3/c24-16-8-19(22(26-9-16)27-11-18-10-25-13-28-18)23(31)29-17-3-5-30(6-4-17)12-15-1-2-20-21(7-15)33-14-32-20/h1-2,7-10,13,17H,3-6,11-12,14H2,(H,25,28)(H,26,27)(H,29,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity towards melanin-concentrating hormone receptor 1 in IMR32 cells				Bioorg Med Chem Lett 15: 4174-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.089 BindingDB Entry DOI: 10.7270/Q2N29WGN
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50171600 (CHEMBL371700 | N-(1-Benzo[1,3]dioxol-5-ylmethyl-pi...) Show SMILES Clc1cnc(NCc2cnc[nH]2)c(c1)C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1 Show InChI InChI=1S/C23H25ClN6O3/c24-16-8-19(22(26-9-16)27-11-18-10-25-13-28-18)23(31)29-17-3-5-30(6-4-17)12-15-1-2-20-21(7-15)33-14-32-20/h1-2,7-10,13,17H,3-6,11-12,14H2,(H,25,28)(H,26,27)(H,29,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against MCH1R IMR32 cells in FLIPR-based assay				Bioorg Med Chem Lett 15: 4174-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.089 BindingDB Entry DOI: 10.7270/Q2N29WGN
					More data for this Ligand-Target Pair