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SMILES: CC(=O)N1C[C@H](O)CC1CN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1

InChI Key: InChIKey=RNJWBAKLCQSABU-XMMISQBUSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50171696   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cGMP-dependent protein kinase


(Eimeria tenella)		BDBM50171696
PNG
(1-((R)-2-{4-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H...)
Show SMILES CC(=O)N1C[C@H](O)CC1CN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1
Show InChI InChI=1S/C27H31FN4O2/c1-18(33)32-17-24(34)14-23(32)16-31-12-8-20(9-13-31)26-15-25(19-6-10-29-11-7-19)27(30-26)21-2-4-22(28)5-3-21/h2-7,10-11,15,20,23-24,30,34H,8-9,12-14,16-17H2,1H3/t23?,24-/m1/s1
UniProtKB/TrEMBL

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PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.20n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against cGMP-dependent protein kinase from Eimeria tenella

Bioorg Med Chem Lett 15: 4570-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.096
BindingDB Entry DOI: 10.7270/Q2416WM9
More data for this
Ligand-Target Pair