BDBM50171723 4-Ethyl-2-(4-hydroxy-phenyl)-quinolin-6-ol::4-ethyl-2-(4-hydroxyphenyl)quinolin-6-ol::CHEMBL198679

SMILES: CCc1cc(nc2ccc(O)cc12)-c1ccc(O)cc1

InChI Key: InChIKey=JHGHNHLKUJDBRE-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50171723   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM50171723 (4-Ethyl-2-(4-hydroxy-phenyl)-quinolin-6-ol | 4-eth...) Show SMILES CCc1cc(nc2ccc(O)cc12)-c1ccc(O)cc1 Show InChI InChI=1S/C17H15NO2/c1-2-11-9-17(12-3-5-13(19)6-4-12)18-16-8-7-14(20)10-15(11)16/h3-10,19-20H,2H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	634	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity for human Estrogen receptor alpha				Bioorg Med Chem Lett 15: 4520-5 (2005) Article DOI: 10.1016/j.bmcl.2005.07.008 BindingDB Entry DOI: 10.7270/Q20864VH
					More data for this Ligand-Target Pair
Estrogen-related receptor alpha (Homo sapiens (Human))	BDBM50171723 (4-Ethyl-2-(4-hydroxy-phenyl)-quinolin-6-ol | 4-eth...) Show SMILES CCc1cc(nc2ccc(O)cc12)-c1ccc(O)cc1 Show InChI InChI=1S/C17H15NO2/c1-2-11-9-17(12-3-5-13(19)6-4-12)18-16-8-7-14(20)10-15(11)16/h3-10,19-20H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human ERalpha				Bioorg Med Chem Lett 17: 4053-6 (2007) Article DOI: 10.1016/j.bmcl.2007.04.068 BindingDB Entry DOI: 10.7270/Q2V124HV
					More data for this Ligand-Target Pair
Estrogen-related receptor beta (Homo sapiens (Human))	BDBM50171723 (4-Ethyl-2-(4-hydroxy-phenyl)-quinolin-6-ol | 4-eth...) Show SMILES CCc1cc(nc2ccc(O)cc12)-c1ccc(O)cc1 Show InChI InChI=1S/C17H15NO2/c1-2-11-9-17(12-3-5-13(19)6-4-12)18-16-8-7-14(20)10-15(11)16/h3-10,19-20H,2H2,1H3	PDB MMDB Reactome pathway KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	634	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human ERbeta				Bioorg Med Chem Lett 17: 4053-6 (2007) Article DOI: 10.1016/j.bmcl.2007.04.068 BindingDB Entry DOI: 10.7270/Q2V124HV
					More data for this Ligand-Target Pair
Estradiol receptor beta (ERβ) (Homo sapiens (Human))	BDBM50171723 (4-Ethyl-2-(4-hydroxy-phenyl)-quinolin-6-ol | 4-eth...) Show SMILES CCc1cc(nc2ccc(O)cc12)-c1ccc(O)cc1 Show InChI InChI=1S/C17H15NO2/c1-2-11-9-17(12-3-5-13(19)6-4-12)18-16-8-7-14(20)10-15(11)16/h3-10,19-20H,2H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity for human Estrogen receptor beta				Bioorg Med Chem Lett 15: 4520-5 (2005) Article DOI: 10.1016/j.bmcl.2005.07.008 BindingDB Entry DOI: 10.7270/Q20864VH
					More data for this Ligand-Target Pair