null

SMILES: O=C1C2C3CC(C=C3)C2C(=O)N1OCCN1CCN(CC1)c1ccccn1

InChI Key: InChIKey=QOFWCJWEWVROMH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50171892   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50171892 (4-[2-(4-Pyridin-2-yl-piperazin-1-yl)-ethoxy]-4-aza...) Show SMILES O=C1C2C3CC(C=C3)C2C(=O)N1OCCN1CCN(CC1)c1ccccn1 |c:6| Show InChI InChI=1S/C20H24N4O3/c25-19-17-14-4-5-15(13-14)18(17)20(26)24(19)27-12-11-22-7-9-23(10-8-22)16-3-1-2-6-21-16/h1-6,14-15,17-18H,7-13H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	382	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Napoli "Federico II" Curated by ChEMBL					Assay Description Inhibition of [3H]-8-OH-DPAT binding to Serotonin 5-HT1A receptor from rat brain cortex				J Med Chem 48: 5495-503 (2005) Article DOI: 10.1021/jm050246k BindingDB Entry DOI: 10.7270/Q2TM79N5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50171892 (4-[2-(4-Pyridin-2-yl-piperazin-1-yl)-ethoxy]-4-aza...) Show SMILES O=C1C2C3CC(C=C3)C2C(=O)N1OCCN1CCN(CC1)c1ccccn1 |c:6| Show InChI InChI=1S/C20H24N4O3/c25-19-17-14-4-5-15(13-14)18(17)20(26)24(19)27-12-11-22-7-9-23(10-8-22)16-3-1-2-6-21-16/h1-6,14-15,17-18H,7-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.51E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Napoli "Federico II" Curated by ChEMBL					Assay Description Inhibition of 0.4 nM [3H]-ketanserin binding to Serotonin 5-HT2A receptor from rat brain cortex				J Med Chem 48: 5495-503 (2005) Article DOI: 10.1021/jm050246k BindingDB Entry DOI: 10.7270/Q2TM79N5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50171892 (4-[2-(4-Pyridin-2-yl-piperazin-1-yl)-ethoxy]-4-aza...) Show SMILES O=C1C2C3CC(C=C3)C2C(=O)N1OCCN1CCN(CC1)c1ccccn1 |c:6| Show InChI InChI=1S/C20H24N4O3/c25-19-17-14-4-5-15(13-14)18(17)20(26)24(19)27-12-11-22-7-9-23(10-8-22)16-3-1-2-6-21-16/h1-6,14-15,17-18H,7-13H2	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Napoli "Federico II" Curated by ChEMBL					Assay Description Inhibition of 1 nM [3H]-mesulergine binding to Serotonin 5-HT2C receptor from rat brain cortex				J Med Chem 48: 5495-503 (2005) Article DOI: 10.1021/jm050246k BindingDB Entry DOI: 10.7270/Q2TM79N5
					More data for this Ligand-Target Pair