null
SMILES: CS(=O)(=O)N1CCCc2cccc(N3CCN(CC3)C(=O)C(Cc3ccc(Cl)cc3)NC(=O)[C@H]3Cc4ccccc4CN3)c12
InChI Key: InChIKey=PMAVVCOIMSCEPP-FICMROCWSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50172067 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [125I]-NDP MSH binding towards human melanocortin 4 receptor | Bioorg Med Chem Lett 15: 4459-62 (2005) Article DOI: 10.1016/j.bmcl.2005.07.035 BindingDB Entry DOI: 10.7270/Q2NV9HTH | |||||||||||
More data for this Ligand-Target Pair |